Treatment failure with propranolol for subglottic haemangioma

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Propranolol for the treatment of subglottic hemangiomas.

INTRODUCTION Infantile subglottic hemangiomas are rare causes of airway obstruction. They begin to proliferate at 1-2 months of age and can cause biphasic stridor with or without respiratory distress. Diagnosis requires direct visualization by direct laryngoscopy and bronchoscopy. Various therapeutic options have been utilized for treatment, including tracheotomy, open surgical excision, laser ...

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Subglottic Hemangioma Treated With Propranolol

Figure 1. Pretreatment tracheobron-choscopy. Figure 2. Pretreatment CTA of the neck. DESCRIPTION A 3-month-old girl child was admitted to the pediatrics service with a 1-month history of respiratory distress and stridor, which had acutely worsened over the previous day and led to a brief episode of apnea. The stridor was biphasic in nature with a more pronounced inspiratory component and was ex...

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Subglottic haemangioma: two infants with laryngeal stridor.

The literature contains records of 18 infants with stridor due to haemangiomata in or just below the larynx. Two of these were reported by Mr. James Crooks in this Journal (Crooks, 1954). Since then he has had three further cases at The Hospital for Sick Children, Great Ormond Street, and I am indebted to him for permission to publish details of two of them, bringing the total number of cases r...

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Subglottic and mediastinal hemangioma in a child: treatment with propranolol.

To the Editor: A 6-month-old girl with upper airway obstruction was evaluated in the emergency room. The patient had been born prematurely (at gestational week 34). Prior to the emergency room visit, she had been treated for gastroesophageal reflux and recurrent respiratory infection. Physical examination revealed laryngeal stridor. All laboratory test results were normal. A CT scan of the ches...

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Propranolol treatment of subglottic hemangiomas: a review of the literature.

Subglottic hemangiomas (SGH), which are rare benign tumors of the airway, are potentially life-threatening conditions that may require intervention. Propranolol appears to be an effective treatment for these tumors and should therefore be a first-line treatment for SGH that require intervention. This review presents the clinical presentation and diagnosis of SGH and discusses current knowledge ...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2019

ISSN: 1757-790X

DOI: 10.1136/bcr-2018-227135